Conclusion: NS seeds showed a decrease in incidence of FN in children with brain tumors with shortening of subsequent LOS which may improve their outcome and thereby quality of life. Larger scale studies are needed to further evaluate the seeds’ potential.
Purpose: Seeds of Nigella sativa (NS) are used to combat various disease conditions through their antibacterial effects. To evaluate the seeds’ potential, we studied their effect on the prevention of febrile neutropenia (FN) in children with brain tumors.
Results: The majority of children 38/40 (95%), of the intervention group, took the seeds for 3-9 consecutive months. Eight out of 372 (2.2%) FN episodes were experienced by children of intervention group compared to controls 63/327 (19.3%) (p = 0.001) and a shorter LOS (median = 2.5 days) vs 5 days in the control group (p = 0.006). Children in both groups belonged to almost same geographical area with similar socio-economic background. Weights of children were almost equal at diagnosis.
Methods: A randomized pretest-post-test control group study including 80 children (2-18 years) with brain tumors undergoing chemotherapy were equally allocated into two groups. Intervention group received 5 g of NS seeds daily throughout treatment while controls received nothing. CBC with differentials, incidence of FN, and LOS were noted on each follow-up.
Keywords: Black seed; Febrile neutropenia; Nigella sativa; Nutrition; Pediatric brain tumors; Pediatric oncology.
Melanie Reid, professor at Lincoln Memorial Universityâs Duncan School of Law
Some U.S. law enforcement officials echoed those observations, saying there is no clear evidence on the ground that such prosecutions have slowed China’s quest for U.S. secrets.
Mo, who is being treated for a rare form of cancer, received a sentence that was even more lenient than the maximum five years laid out in his plea deal. Five others indicted in the plot remain free in China, out of the reach of U.S. law enforcement. And though the FBI suspected the Chinese government was involved in the thefts, it was never able to prove the link.