Can I Give My Dog Prednisone And CBD Oil

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When something is wrong with your doggo, pet owners often find themselves quickly spiraling into a panic. A timely trip to the veterinarian will often leave dog owners feelings more calm in one sense, per say, but potentially more concerned in other aspects. What are these medications? Are they all really necessary? This article will show you what to give your dog instead of Prednisone for inflammation-related conditions, such as allergies and skin problems. Explore natural alternatives to Prednisone. Prednisone for dogs – a standard solution used by veterinarians everywhere to prevent dogs from getting sick. Read to know more here.

Can I Give My Dog Prednisone And CBD Oil

When something is wrong with your doggo, pet owners often find themselves quickly spiraling into a panic. A timely trip to the veterinarian will often leave dog owners feelings more calm in one sense, per say, but potentially more concerned in other aspects.

What are these medications? Are they all really necessary? Why is there a laundry list of associated side effects?

Again, we understand what a worrisome time this can be for you. First, your four-legged love pup is sick, which is bad even on its own. But to add to that, you now have to make difficult choices regarding which medication is the right one for your pup.

The fine print may read that your dog’s allergy drug may also have negative, long-term side effects. Unfortunately, many drugs that we use to help our dogs feel better may have some serious side effects. This might not make sense, but it is the reality of many conventional medications.

I n this article, we are breaking down the popular steroid drug – prednisone. We hope we can answer all of your questions and concerns regarding prednisone. We want to help our readers become better educated on the medication so that they can make the best decisions as possible in terms of their pup’s health.

What is Prednisone

Prednisone is a synthetic steroid that is commonly prescribed to treat a wide variety of illnesses. In fact, you may have heard of this steroid before as it’s commonly prescribed to humans.

Prednisone is an anti-inflammatory drug and plays a key role in reducing inflammation in dogs and humans alike.

For instance, prednisone is often prescribed to treat inflammation and inflammatory conditions like neoplasia, asthma, arthritis, Addison’s disease, and anaphylactic shock.

What are Corticosteroids

Corticosteroids are often referred to as steroids. Cortisone, a corticosteroid, for example, is a steroidal hormone that is produced in the adrenal cortex of vertebrates.Corticosteroids are involved in many activities in your dog’s body, such as:

  • Stress response
  • Nutrient metabolism
  • Control of inflammation
  • Immune system response

These steroid hormones can too be produced synthetically, often in the form of prednisone.

Prednisone is very similar to cortisol (a naturally-produced adrenal hormone), but more potent. Cortisol is released in response to a stress occurrence. This release is regulated by the hypothalamic-pituitary-adrenal axis (HPA axis). Essentially what happens is this: when the body senses stress, the hypothalamus starts a chain reaction that leads to a release of cortisol by the adrenal glands.

When a dog has an illness that lowers natural and healthy levels of cortisol, a synthetic form of cortisol (like prednisone) is often required.

What is a Steroid

Steroids are synthetic drugs that are formulated to resemble the naturally produced cortisol and are used typically for medicinal purposes.

But aren’t steroids what people use illegally in sports or competition? These steroids are anabolic steroids, formulated to resemble testosterone.

However, steroids are also important in Western medicine to treat individuals suffering from a wide range of conditions.

Prednisolone Who

Prednisone and prednisolone are corticosteroids that are used in treating inflammation and autoimmune diseases. They can help regulate the immune system.

Once a pet parent administers the prednisone, the dog’s liver metabolizes the medication into prednisolone.

If your pup has a pre-existing live condition, or any form of liver dysfunction for that manner, or even high liver enzymes, then your vet will likely prescribe prednisolone instead of prednisone.

By prescribing prednisolone, the vet can ensure that your pup is able to absorb and process the drug safely and effectively.

Typical Prednisone Use

Prednisone is typically used in the treatment of the following ailments:

  • Lupus
  • Asthma
  • Allergies
  • Skin diseases (eczema, itchy skin, dermatitis)
  • Autoimmune disease
  • CNS disorders
  • Cancer
  • Liver conditions
  • Anaphylactic shock
  • Addison’s disease
  • Cushing’s disease
  • Arthritis-associated joint pain
  • Inflammatory orthopedic conditions

Prednisone Dog Side Effects

Common side effects of prednisone include:

  • Vomiting
  • Diarrhea
  • Skin infections
  • Increased hunger/thirst
  • Skin infections
  • Panting

Prednisone Side Effects: The Long Term

If your vet prescribes prednisone for a long duration ( > 4 months), make sure that you are regularly taking your pup to see the vet to monitor long-term effects, like liver and kidney dysfunction.

Here’s a list of potential adverse effects of long-term prednisone and prednisolone usage:

  • Diarrhea
  • Lethargy
  • Vomiting
  • Pancreatitis
  • Gastric ulcers
  • Muscle weakness
  • Increased risk of infection
  • Muscle weakness
  • Urinary tract infections
  • Development or worsening of diabetes

Administering Prednisone to Your Dog

Most vet medical experts state that the use of prednisolone and prednisone should be used only for a short term and more so even at small doses to reduce the possibility of potential adverse reactions.

You may not notice one specific side effect of prednisone. However, that one little symptom can turn into multiple overnight. This is why it’s extremely important for dog parents to be aware of the potential side effects to be able to know what to look for.

Common doses of prednisone and prednisolone are:

  • 1 mg/lb to suppress the immune system
  • 0.5 mg/lb for anti-inflammation

Your vet will take into consideration your dog’s specific condition and needs to determine the exact dose your pup will need.

Furthermore, it’s extremely important that pet owners do not miss a dose when administering the steroid.

Prednisone for dogs must be given at the same time of the day (or as close as possible to the same time) and at even time intervals (i.e. every 12 hours).

Again, prednisone is used when the body is not sufficiently making enough cortisol on its own. However, do note, prednisone is not intended for permanent use for the deficiency.

Natural Alternatives for Dogs

Luckily, there are other options. As dog parents we are fortunate enough to be living in a time where we have natural alternatives available.

Everyday, more holistic options are making way in the world of natural remedies (hashtag grateful).

1. CBD

Cannabidiol (CBD) is a wonderful, natural, non-toxic option for your four-legged friend. Here, at Petly CBD, we’ve got what you need. CBD Treats? Yep. Hemp CBD Oil? Yep.

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Although CBD is our favorite all-natural remedy, we want to provide you pet parents with information on other supplemental herbs that can benefit your doggo.

2. Turmeric

Turmeric is a great herbal solution for a wide array of inflammatory conditions. It has an anti-inflammatory effect without the potential toxic adverse effects. Turmeric is also great for pet owners (aka you)!

3. Yucca Root

This herbal supplement is definitely one you want to look into. Yucca root contains beneficial levels of the following:

  • Niacin
  • Calcium
  • Iron
  • B Vitamins
  • Vitamin C
  • Magnesium
  • Phosphorus
  • Beta-carotene

Furthermore, studies have shown that yucca root alleviates allergies and arthritis and joint pain. Also, yucca root has been shown to boost your pup’s appetite.

However, do note that you should not give your pup yucca root on a daily basis. Too much yucca root may potentially irritate their digestive tract.

4. Echinacea

This natural herb is a great way to give your pup’s immune system a boost. It’s best to use echinacea on and off for optimal results.

5. Licorice Root

Have you heard of this incredible root? Well, get ready to be amazed. Licorice root contains glycyrrhizin (which functions as a natural corticosteroid). The herb stimulates the secretion of hormones in the adrenal gland. Aka, it aids in the production of the same hormones that prednisone aims to produce, except licorice root is all-naturale. It acts as an anti-inflammatory agent and reduces swelling. WIN. It helps ease skin conditions and common skin allergy symptoms.

6. Ginger

Another excellent way to reduce inflammation and the associated pain and swelling? Ginger, my friends. The herbal solution blocks the body from producing chemicals.

7. Comfrey

This herb can reduce bone inflammation in an effective, healthy, and you guessed it – in a natural way.

8. Diet

I t’s easy to forget the importance of a healthy diet (in both us humans and our fur babies). We should think of food as a means of healing. Raw food diets have the necessary nutrients for your doggo to live their best life. Consult with your vet to devise a raw food diet that is best for your pup.

Prednisone for Dogs: Final Thoughts

At the end of the day, we understand your needs to ensure that your pup is living their best life possible. For this to be possible, as paw parents, we have to know as much as possible about what we are giving our fur babies.

Understanding the dangers of conventional medications is not an effort to concern or scare you, but rather to educate you on what’s going on out there. So all in all, don’t forget to consider a holistic, natural source of healing for your pup. You won’t regret it one bit

Prednisone Alternatives For Dog: What to Give Your Pet Instead?

Steroids are an important class of medication that have been used to treat human conditions for decades. This class of drugs proves to be just as effective in handling veterinary allergies and inflammatory diseases.

Steroids, such as Prednisone, are employed to alleviate pet allergies and treat asthma-like symptoms, among other conditions.

However, despite its usefulness, Prednisone is not intended for long-term use. Prednisone therapy requires a list of alternatives ready to prevent Steroid addiction.

What is Prednisone?

Prednisone is an oral steroid used to treat autoimmune and inflammatory conditions. It’s a glucocorticoid that diminishes the effects of the immune system by inhibiting the migration of polymorphonuclear leukocytes and reversing increased capillary permeability that is indicative of an inflammatory process.

Prednisone is used in humans and the veterinary population to treat asthma, gout, COPD, Meniere’s disease, lupus, shingles, hives, allergies, and even migraine and cluster headaches. Its immunosuppressive activity may be exercised in organ transplantation, preventing graft rejection.

The medication has also been employed as an antitumor drug and adjunct to cancer therapy. Prednisone is said to manage hypercalcemia caused by cancer activity.

Prednisone may be used to prevent heart failures in patients with renal insufficiency and high blood pressure.

Prednisone is synthetic, FDA-approved, and has a delayed release pattern.

Can Dogs Take Prednisone?

Glucocorticoids are the most common steroids used to treat canine inflammatory disorders and CBD is commonly used to treat allergies on dogs.

When treating a dog with a steroid, it’s crucial to keep the duration of its use in mind. Prednisone may be administered systematically (orally), topically, or by infusion. In any case, the steroid should only be used for short periods to prevent dependence and side effects.

The safest way to take Prednisone to your dog is to apply it topically, using a patch, gel, or cream. Prednisone eye drops may also be used to treat itchy, red eyes associated with an allergy. Long-term use of Prednisone is not advised.

Prednisone for Dogs Dosage

The prednisone dosage depends on the condition it is to be used to treat. It also depends on the severity of the inflammation or allergy and the use of other veterinary medications. Generally speaking, a low dose of Prednisone is needed for anti-inflammatory actions, while a much higher amount is required to suppress the immune system but is a lot more difficult to wean off.

The dosage range for anti-inflammatory and immunosuppressive action is 0.5-1.0mg/lbs (1) (2). For a dog weighing 50 pounds with a mild rash, administer 25mg of Prednisone once a day for three days, then taper the medication by adjusting the dose to once in two days before finally ceasing the medication.

However, if it is used as an immunosuppressive agent following surgery, you may use 50mg of prednisone for a similar duration.

Prednisone dosage should not be extrapolated to Prednisolone because the former undergoes metabolism by the liver, called the first-pass effect.

Side Effects of Prednisone for Dogs

The side effects of prednisone in dogs may be divided into short-term and long-term effects. The long-term effects remain even after the medication is no longer in use.

Short term effects of Prednisone:

  1. Frequent urination and thirst: Prednisone is a drug that influences the production of cortisol by the adrenal glands positioned on the kidneys. These glands are also responsible for the sensation of thirst and water balance. Stimulation of these glands will cause an increase in thirst, which will then spur frequent urination.
  2. Increased appetite and weight gain: cortisol stimulates the metabolism of fats and carbohydrates, releasing stored energy for your cells to boost your activity. However, your brain receives a signal to increase food intake leading to weight gain.
  3. Slower wound healing: when a dog’s skin is cut, the blood vessels in that area immediately constrict to reduce the amount of blood lost. The blood loss triggers the immune system, which sends leucocytes to the injury site. Prednisone prevents the migration of leucocytes involved in wound healing and inflammation.
  4. Higher risk of infection: while the immune system remains compromised, foreign or opportunistic pathogens that make up the microbiome may increase and initiate an infection.
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Long term effects of Prednisone:

  1. Diabetes: long term administration of high doses of prednisone is known to cause hyperglycemia in dogs. The elevated blood sugar levels persist one week to four months after discontinuation of prednisone (3). Studies suggest that prednisone overuse may irreversibly damage the pancreatic cells responsible for glucose metabolism.
  2. Bone demineralization: cortisol causes calcium to be absorbed from the bone into the blood, a process called demineralization of bone. This demineralization is peculiar to the lumbar spine. A dog population was treated with 2mg/kg of Prednisone for 30 days and witnessed a 14% loss in bone mass (4).
  3. Behavioral changes: dogs treated with Prednisolone and its analog display more aggressive tendencies, especially in the presence of food. They are also more restless and more prone to barking than dogs being treated with other classes of medications. Prednisone use is also associated with aversiveness and reduced confidence in canines (5).
  4. Adrenal insufficiency: overstimulation of the adrenal glands, caused by overuse of corticosteroids, will reduce the production of cortisol. This may be likened to dependence. In this case, once Prednisone is ceased, an adrenal crisis may occur (6).

Alternatives to Give Your Dog Instead of Prednisone

Yucca Shidigera

Yucca shidigera is a Native American plant grown for ornamental purposes. Aside from its aesthetical uses, it may relieve pain, reduce inflammation, improve digestion and circulation. It is also rumored to treat high blood pressure, diabetes, arthritis, amongst others.

Turmeric

Turmeric is said to have anti-oxidant, anti-inflammatory, and healing properties in humans and dogs. The spice is also safe for coloring in both human and dog food. The question of its anti-inflammatory potency in dog food is directly linked to its dosage.

Dog treats typically contain a sparse amount of turmeric as a flavor enhancer or even to improve the color of the treat. Still, these dosages are too little to sprout any anti-inflammatory properties.

Unfortunately, no studies have been performed using higher doses of turmeric, so it’s difficult to ascertain whether turmeric will indeed reduce inflammation in dogs.

CBD Oil

CBD oil is a natural extract obtained from Cannabis sativa. It only contains trace amounts of THC in its natural form, so you won’t get high off of it. A good quality CBD oil for your dog has the potential to relieve itching, inflammation, pain, and restlessness. In a recent study, CBD was administered to a canine population. The scientists observed that the dogs experienced a slight upregulation of IL-10, an anti-inflammatory cytokine, and a more pronounced downregulation of IL-6 and 1L-8, the pro-inflammatory cytokines (7).

Thus we may infer that CBD can modulate the immune system. This may become a novel therapy for allergies and immune reactions in pets.

CBD and Prednisolone: Can They Be Taken Together?

Both Prednisone and CBD are potentially effective options for pet allergies. However, concomitant use of these medications is not advised. Prednisone inhibits cytochrome P450, just like CBD.

This means that CBD may delay the systemic clearance of Prednisone. The increased serum Prednisone levels increase the risk of long-term side effects, even with short-term use.

However, since pulse therapy is advised with corticosteroids, CBD may fill the spaces. When administering CBD and Prednisone, ensure that you cease one treatment before initiating the other. Certain types of drugs and CBD shouldn’t be mixed or administered within the same day, and Prednisone is one of them.

Conclusion

Prednisone is an oral steroid used to combat inflammation and allergic reactions in dogs. While it can be a decent source of relief when used short-term at appropriate doses, long-term use or giving Prednisone without prior consultation with a veterinarian can do more harm than good.

If you’re looking for natural alternatives to Prednisone for your dog, try natural health supplements like turmeric or CBD oil. CBD is the most versatile and best-researched anti-inflammatory compound of all alternative options mentioned in this article. It’s also the only compound that regulates the functioning of your dog’s endocannabinoid system — which is its first line of defense against environmental stressors.

With a properly working endocannabinoid network, your dog’s immune system may return to balance, bringing desired results in a longer period — but with a better safety profile.

Sources:

  1. Sauerbrey, M. L., Mullins, M. N., Bannink, E. O., Van Dorp, T. E., Kaneene, J. B., & Obradovich, J. E. (2007). Lomustine and prednisone as a first-line treatment for dogs with multicentric lymphoma: 17 cases (2004-2005). Journal of the American Veterinary Medical Association, 230(12), 1866–1869. [1]
  2. Weinfurter, M. (2021). Prednisone for Dogs: Side Effects, Dosage, And Alternatives. Relievet. Retrieved from: https://www.relievet.com/blogs/tips/prednisone-for-dogs-side-effects-dosage-and-alternatives
  3. Zeng, Y., Ricordi, C., Lendoire, J., Carroll, P. B., Alejandro, R., Bereiter, D. R., Tzakis, A., & Starzl, T. E. (1993). The effect of prednisone on pancreatic islet autografts in dogs. Surgery, 113(1), 98–102.
  4. Costa, L. A., Lopes, B. F., Lanis, A. B., De Oliveira, D. C., Giannotti, J. G., & Costa, F. S. (2010). Bone demineralization in the lumbar spine of dogs submitted to prednisone therapy. Journal of veterinary pharmacology and therapeutics, 33(6), 583–586.[2]
  5. Notari, L., Burman, O., & Mills, D. (2015). Behavioural changes in dogs treated with corticosteroids. Physiology & behavior, 151, 609–616. [3]
  6. Broersen, L. H., Pereira, A. M., Jørgensen, J. O., & Dekkers, O. M. (2015). Adrenal Insufficiency in Corticosteroids Use: Systematic Review and Meta-Analysis. The Journal of clinical endocrinology and metabolism, 100(6), 2171–2180. [4]
  7. Gugliandolo, E., Licata, P., Peritore, A. F., Siracusa, R., D’Amico, R., Cordaro, M., Fusco, R., Impellizzeri, D., Di Paola, R., Cuzzocrea, S., Crupi, R., & Interlandi, C. D. (2021). Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood. Veterinary sciences, 8(9), 185. [5]
Livvy Ashton

Livvy is a registered nurse (RN) and board-certified nurse midwife (CNM) in the state of New Jersey. After giving birth to her newborn daughter, Livvy stepped down from her full-time position at the Children’s Hospital of New Jersey. This gave her the opportunity to spend more time writing articles on all topics related to pregnancy and prenatal care.

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Prednisone for Dogs

No matter who you are, your dog quickly becomes a treasured member of the family, and like any family member, they will get sick at some point. And, just like any other member of the family, you will go above and beyond to help them get better. One treatment for this is prednisone, a standard solution used by veterinarians everywhere. However, is it all it’s cracked up to be, or is there a better way?

What is Prednisone?

Prednisone is a steroid used to treat inflammation in your dog while also assisting its immune system. It is stronger than the naturally released cortisol, and it is converted to prednisolone in your dog’s liver . If your dog has a weak liver function , vets may skip prednisone altogether, and instead prescribe prednisolone to save on conversion.

As it can treat a wide range of diseases and conditions, prednisone is a popular option for ensuring your dog gets back to its silly and energetic self. However, as with many treatments out there, it does come with side effects that you may want to avoid.

Why is Prednisone Bad for Dogs?

These side effects can range from increased thirst to lethargy, and while these may not be considered too extreme, they can still have adverse effects on your dog’s health . This is especially true when side effects compounds. For example, increased thirst can lead to more frequent urination, but as another side effect of prednisone is infrequent urination in dogs, it could cause an infection .

Other side effects include increased appetite , which can cause discomfort, and it can also take longer for wounds to hea l, which is especially concerning if your dog gets sick or injured easily during his or her routine walk.

Furthermore, vomiting and diarrhea are other possible side effects, and this can happen even if your dog does not overeat during mealtime.

There is also a chance that it could affect their overall behavior, becoming more aggressive. After all, no one wants their dog to snap, bark, or growl at guests, strangers, or even their family members, and if you have other pets and small children, this could be a cause for concern.

There are also long-term risks associated with prednisone prescriptions and treatment, primarily if you use the steroid for an extended time. Conditions such as Addison’s disease, Cushing’s disease, diabetes, heart problems, or even heart attacks are potentially fatal issues, so it’s worth understanding alternatives to using prednisone to treat your dog’s health problems.

Looking for delicious treats that will also alleviate your dog’s pain and anxiety? Dope Dog has everything you need to make your dog happy

Why Should You Use CBD Instead?

Using CBD for treatment is a superb and all-natural alternative to pharmaceutical medications. These solutions, which you can find on the Dop Dog store, can get your dog back to perfect health just as quickly, and without the same issues that you might encounter with prednisone.

Pros

It’s non-toxic

As an all-natural ingredient, you can trust that CBD treatment is entirely non-toxic . This helps reduce the risk of side-effects and will focus only on treating whatever issues your dog may suffer from.

It’s more affordable.

If you thought medicine was expensive for humans, medicine for dogs, or any pet, is on a whole other level. As a dog owner, you know you will do anything it takes to ensure your dog gets back to its usual self, so you are willing to spend whatever you need to make sure that happens.

CBD treatments are more affordable than other medical treatments , which is excellent news for anyone on a budget or looking for a natural and affordable solution. Plus, with the extra money you save on medicine, you can start planning your next doggy-and-you vacation. We hear the Rockies is terrific this time of year.

It treats many common problems.

From cancer pain to anxiety, CBD can treat a range of issues your dog might encounter. As it is all-natural, there is no need to worry about extreme side effects. It can also fight off potential cancer cells, reduce aggressive behavior, ease anxiety , and help with arthritis. This ensures that your dog will bound around the park for many, many years to come.

Your dog won’t get high off it.

There is zero THC , the psychoactive component of cannabis; you don’t need to worry about your dog getting high and eating all of the snacks in the cupboard.

Cons

While CBD can be useful for treating your dog for a range of problems, illnesses, and diseases, it is not entirely perfect . As with anything you allow your dog to ingest, you must understand the cons as well as the pros.

It can still make them lethargic.

As your dog will not be used to CBD as medication, there is a chance that it may become less energetic when you start using it . Because of this, it’s worth starting the treatment in small doses to get them used to the effects.

You can still encounter problems if you give them too much.

Likewise, giving your dog too much CBD treatment can have effects on your pooch. You must follow the application guidelines to prevent this from happening.

Even with these cons, there are still more pros for using CBD as a treatment for your dog . With this in mind, it’s worth considering your options the next time your dog appears to be suffering from anxiety or more significant problems to see whether CBD is the solution.

Looking for quality CBD products? Dope Dog has a wide selection to keep your canine companion smiling for life.

Doggy Treats

If your dog is sick or ill and you want an all-natural remedy to get them back on their feet, so you can start going on adventures again, then take the time to consider a CBD rather than prednisone. For all your doggy’s CBD needs, don’t forget to check out the Dope Dog store , as well as embrace the wealth of detailed information on this blog!

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