Can CBD Oil Cure Melanoma

CBDISTILLERY

Buy CBD Oil Online

Over the last decade, much attention has been focused on compounds from Cannabis sativa in treating a variety of diseases including cancer. This study examines the abilities of two different cannabidiol oils to decrease the migration and invasion of melanoma cells in vitro. Skin cancers are the most common cancers in the world. While malignant melanoma is the least common type of skin cancer, it is the deadliest. Patients diagnosed with stage IV disease have only a 15-20% five-year survival rate even with aggressive multimodal treatment, demonstrating the need for additional therapeutic options. Because melanoma is often fatal when it has metastasized, an ideal treatment would not only decrease the proliferation and viability of the cancer cells but would also decrease their ability to spread via these mechanisms. While the medicinal value of Cannabis remains controversial because of the psychotropic effects of the most well-known cannabinoid compound, tetrahydrocannabinol, cannabidiol (CBD) is one of the many compounds in Cannabis that does not produce the high normally associated with the marijuana plant. Cannabidiol has been shown to decrease melanoma growth and viability in vitro and in vivo. The first hypothesis of this study is that CBD oil will also decrease migration and invasion of melanoma cells in vitro. Further, because the Cannabis plant contains over one-hundred-thirteen different cannabinoids and other compounds known to have health benefits, the second hypothesis of this project is that extracted CBD, Charlotte’s Web, oil will have a greater effect on melanoma cells than purified CBD alone. To test these hypotheses, migration assays using a scratch-wound protocol and invasion assays using a modified Boyden chamber assay were used. In the scratch wound assay the purified CBD performed significantly better than the Charlotte’s Web CBD oil at the highest concentration used; however, in the invasion assay there was no significant difference between the performance of the two oils. Our data suggests that both oils are effective in reducing melanoma cells metastatic potential in vitro, and their use as adjuvant or alternative therapies warrants further study. CBD’s Impact on Melanoma Cells Hannah Yohe ’21 has read the news articles and seen the new businesses popping up touting the benefits of medical marijuana and cannabidiol, or CBD. She’s watched Can CBD Hemp Cream Help to Cure Skin Cancer? Because of its numerous applications, cannabidiol (CBD) is now an excellent therapeutic choice for skin, particularly skin cancer. It was once

Can CBD Oil Cure Melanoma

Dr. Lori L. Hensley

Abstract

Over the last decade, much attention has been focused on compounds from Cannabis sativa in treating a variety of diseases including cancer. This study examines the abilities of two different cannabidiol oils to decrease the migration and invasion of melanoma cells in vitro. Skin cancers are the most common cancers in the world. While malignant melanoma is the least common type of skin cancer, it is the deadliest. Patients diagnosed with stage IV disease have only a 15-20% five-year survival rate even with aggressive multimodal treatment, demonstrating the need for additional therapeutic options. Because melanoma is often fatal when it has metastasized, an ideal treatment would not only decrease the proliferation and viability of the cancer cells but would also decrease their ability to spread via these mechanisms. While the medicinal value of Cannabis remains controversial because of the psychotropic effects of the most well-known cannabinoid compound, tetrahydrocannabinol, cannabidiol (CBD) is one of the many compounds in Cannabis that does not produce the high normally associated with the marijuana plant. Cannabidiol has been shown to decrease melanoma growth and viability in vitro and in vivo. The first hypothesis of this study is that CBD oil will also decrease migration and invasion of melanoma cells in vitro. Further, because the Cannabis plant contains over one-hundred-thirteen different cannabinoids and other compounds known to have health benefits, the second hypothesis of this project is that extracted CBD, Charlotte’s Web, oil will have a greater effect on melanoma cells than purified CBD alone. To test these hypotheses, migration assays using a scratch-wound protocol and invasion assays using a modified Boyden chamber assay were used. In the scratch wound assay the purified CBD performed significantly better than the Charlotte’s Web CBD oil at the highest concentration used; however, in the invasion assay there was no significant difference between the performance of the two oils. Our data suggests that both oils are effective in reducing melanoma cells metastatic potential in vitro, and their use as adjuvant or alternative therapies warrants further study.

See also  CBD Gummies Expire

CBD’s Impact on Melanoma Cells

Hannah Yohe ’21 has read the news articles and seen the new businesses popping up touting the benefits of medical marijuana and cannabidiol, or CBD. She’s watched as friends and family purchase CBD products that offer promises of helping with joint inflammation or anxiety. While the York College Biology major is a believer in the health benefits of medical marijuana, she knew there was a lot of research ahead.

“I wanted to find the gaps in what still needed to be studied,” she says. “I’m really interested in this topic and thought I had an opportunity to dive into research while it’s still early in the process.”

Yohe found that melanoma, a form of skin cancer that can easily spread to other organs, was an area that had a lot of research gaps. York College had melanoma cells available in the lab, so Yohe just had to work to get access to CBD for her independent research project.

“You can’t just go out and buy CBD, despite what you see on the shelves of health stores or even at the gas station,” she says. “There are often other additives in it, and you need a pure form to be able to conduct research. Sigma-Aldrich biotechnology provided lab quality CBD for Yohe’s research. Finally, she could get to work.

A lot of people still have uncertainty about the health benefits of medical marijuana because they don’t understand it, Yohe says. While there are more than 100 chemicals in cannabis, the two most common are THC (short for tetrahydrocannabinol) and CBD. Both can be found in marijuana and hemp, although marijuana has more THC, which produces the high, and hemp has more CBD, which has other medicinal properties without the high.

The FDA has approved one CBD-based drug. Epidiolex is a treatment for several severe forms of rare childhood epilepsy. The National Institutes of Health clinical trials database shows more than 160 trials involving CBD that are either active or recruiting.

“It’s a subject that has a lot of opportunity for understanding,” Yohe says. “Getting into the research now is a great foundation for the work I could be doing in my career.”

While many people think of medical marijuana as a treatment for symptoms, such as anxiety or inflammation, Yohe found that CBD was actually instrumental in treating the root of melanoma. Other medical research shows CBD reduces the size of brain tumors, decreases growth in colon cancer and pancreatic cancer, and slows down blood vessel formation.

See also  CBD Gummies El Paso

Yohe’s research backed up her theory that CBD could reduce the melanoma, but some of her experiments were cut short because of COVID-19. Despite not getting to all of her proposed experiments, she was able to use lab equipment specific to her research and learn some fascinating things about CBD.

“A lot of things we learn in the classroom can be theoretical, so you don’t see them in real life,” she says. “It’s cool when you can do the experiment yourself and get actual data and see that this stuff is real. We can test our theories and learn by doing.”

Can CBD Hemp Cream Help to Cure Skin Cancer?

Because of its numerous applications, cannabidiol (CBD) is now an excellent therapeutic choice for skin, particularly skin cancer. It was once exclusively accessible in novelty or vitamin stores but is now widely available at grocery shops, drugstores and fitness clubs. CBD is beneficial in several ways. It can address practically any issue, from mental to physical wellness.

Today, several high-quality CBD hemp creams for joint pain are available from reliable brands. Before we can comprehend the beneficial effects of hemp cream for treating or preventing skin cancer, we must first define it.

What Exactly Is CBD Hemp Cream?

The cannabis plant yields cannabidiol. This plant is scientifically called Cannabis Sativa, and it is more often known as the hemp plant. While many people are aware of the plant because of its psychotropic effects, the cannabis plant is increasingly being seen positively because of the numerous health benefits it delivers.

CBD hemp cream is a topical skincare product containing hemp CBD oil. Pure CBD hemp cream is distinct in that it is devoid of THC, the chemical that causes intoxication. CBD Topicals are administered directly to the skin that requires treatment. Pain treatment roll-ons and unfiltered CBD oil are some alternative topicals. These medicines provide pain relief by being absorbed via the skin and connecting to receptors in the lower layers of the skin.

In general, CBD skin lotions are applied directly to an afflicted part of the body. The creams and lotions can give treatment at both the surface and deeper layers of the muscles. In rare situations, they can also assist with relaxation and sleep. CBD is also available as balms, salves and transdermal patches, in addition to creams.

Hemp CBD Cream For Skin Cancer

Skin cancer has been the subject of much research. Here are a few of the most common treatment options:

  1. Excisional surgery
  2. Mohs micrographic surgery
  3. Cryotherapy
  4. Curettage
  5. Radiation therapy
  6. Chemotherapy
  7. Photodynamic treatment

Many contemporary cancer medicines are effective, but they can be pricey and, in some cases, hazardous.

Cannabis is gaining the limelight as a natural medicine for several diseases, but clinical studies are lacking because of its long prohibition. However, numerous research over the last decade shows findings concerning CBD and THC and their effects on the human body.

Cannabinoids’ therapeutic benefits are linkable to their effects on the human body’s endocannabinoid system (ECS). Though further study is needed, several studies have revealed that cannabis oil has anti-cancer properties. Though the benefits of CBD on other forms of cancer have received less attention, limited studies have yielded promising outcomes.

See also  How To Make CBD Oil With Coconut Oil

Numerous research exists on the efficacy of CBD topicals in treating skin cancer. Several studies have shown that using oil in conjunction with other cancer treatment methods can help reduce tumor formation swiftly. Many studies have also found that taking CBD oil as a topical can improve the efficacy of cancer treatments in some situations.

A THC and CBD combination increased autophagy (the breakdown of unnecessary cell components while maintaining good cells) in malignant cells, according to a 2015 study published in the Journal of Investigative Dermatology. It also promoted cell death and prevented cancer cells from spreading. To make the most use of CBD in cancer therapy, studies on how to administer the right amount of CBD to the patient and other potential administration methods have been conducted.

How to Apply CBD Cream to Treat Skin Cancer

CBD hemp cream majorly consists of hemp-derived CBD oil. It is, however, not a proven cancer therapy. There have been few clinical trials and scientific investigations on CBD oil for skin cancer. However, multiple studies have shown that it might have anti-cancer properties. Cancer patients might benefit from the anti-inflammatory and pain-relieving properties of cannabidiol topicals, regardless of any value in treating the skin cancer itself.

When looking for CBD oil, look for a provider that uses high-quality hemp-derived cannabis oil. CBD products should be checked for purity and efficacy by a third-party lab, and additional components should not be there. There is no standard dose for cannabidiol products, so always follow your doctor’s instructions. Dosing instructions differ based on the concentration of the substance you chose, so consult the box.

Other Benefits of CBD Hemp Cream

According to research, CBD skin lotions can help with several diseases.

  1. Acne, psoriasis and eczema

According to the American Academy of Dermatology Association (AAD), CBD’s anti-inflammatory effects might benefit in the treatment of acne, psoriasis and eczema.

A rat study discovered that some CBD compounds have long-term therapeutic effects on inflammation and arthritis-related behaviors.

  1. Neuropathy of the periphery

A study discovered that CBD topicals relieve pain in persons suffering from peripheral neuropathy — a nerve disease that causes discomfort, numbness and weakness in the feet and hands.

According to a 2019 study, patients who suffer from temporomandibular dysfunction (TMD) might notice an improvement in their condition after consuming CBD products. TMD can cause discomfort and stiffness in and around the jaw.

While CBD cream is not a cure-all for skin cancer, it can help with pain and inflammation. CBD has also been found in research to help relieve the ill effects of chemotherapy. In one study, ingesting CBD reduced chemotherapy-induced nausea and vomiting.

Before using CBD, it is vital to contact your doctor. Although cannabidiol is generally safe, it might interact with some medications. Several CBD news sources suggest consulting your doctor about the proper starting dose, then following up when you start to observe the effects of the prescription so you can make any required changes. Finding the ideal dosage might necessitate some trial and error.

Be aware that CBD has the potential to cause side effects. They are, however, frequently minor and include symptoms such as diarrhea, drowsiness and appetite disorders.

How useful was this post?

Click on a star to rate it!

Average rating 4 / 5. Vote count: 1

No votes so far! Be the first to rate this post.